Description

Methyl 5-Bromopyrazine-2-Carboxylate is a high-purity brominated pyrazine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its reactive bromine and ester functional groups, which enable precise molecular modifications in complex chemical architectures. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the pyrazine core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as components for organic light-emitting diodes (OLEDs) or conductive polymers.
• Chemical Biology Probes: Utilized to synthesize molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	Methyl 5-Bromopyrazine-2-Carboxylate
CAS No.	210037-58-4
Molecular Formula	C6H5BrN2O2
Molecular Weight	217.02 g/mol
Synonyms	5-Bromopyrazine-2-carboxylic acid methyl ester; Methyl 5-bromopyrazine-2-carboxylate; 2-Bromo-5-methoxycarbonylpyrazine; 5-Bromo-2-pyrazinecarboxylic acid methyl ester; 210037-58-4; Methyl 5-bromo-2-pyrazinecarboxylate; 5-Bromopyrazine-2-carboxylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our Methyl 5-Bromopyrazine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Any single unknown impurity	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	<20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.