Description

6-Hydroxy-7-Methoxydihydroligustilide is a specialized dihydrophthalide derivative, a key chemical intermediate and reference standard of significant interest in advanced organic synthesis and analytical research. Its value lies in its unique structural framework, which serves as a crucial building block for the development of novel pharmaceutical compounds and fine chemicals. This product is essential for research and development laboratories, pharmaceutical manufacturers, and suppliers of high-purity chemical standards seeking reliable, high-quality intermediates.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological and cardiovascular pathways.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for method development, validation, and quality control of related compounds in herbal extracts and finished products.
• Biochemical Research: Employed in pharmacological and metabolic studies to investigate structure-activity relationships (SAR) and biological mechanisms of dihydrophthalide derivatives.
• Fine Chemical Synthesis: Acts as a versatile synthon for constructing complex molecular architectures in medicinal chemistry and material science research.
• Natural Product Analysis: Utilized as a standard for the identification and quantification of ligustilide derivatives in traditional medicine extracts, such as those from *Angelica sinensis* and *Ligusticum* species.

Basic Information

Product Name	6-Hydroxy-7-Methoxydihydroligustilide
CAS No.	210036-09-2
Molecular Formula	C13H16O4
Molecular Weight	236.26 g/mol
Synonyms	6-Hydroxy-7-methoxydihydrophthalide; Dihydro-6-hydroxy-7-methoxyligustilide; (3Z)-3-Butylidene-6-hydroxy-7-methoxy-1(3H)-isobenzofuranone; 6-Hydroxy-7-methoxy-3-butylidene phthalide; Ligustilide derivative; DHLG; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 6-Hydroxy-7-Methoxydihydroligustilide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods (NMR, MS) for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.