Description

1-Boc-4-(4-Chloro-Benzoyl)-Piperidine is a high-purity, protected piperidine derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in providing a versatile, reactive scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working in the pharmaceutical, agrochemical, and fine chemical industries who require reliable building blocks for drug discovery and synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new therapeutic candidates.
• Peptidomimetic Synthesis: Serves as a constrained scaffold for creating peptide analogs and mimetics with improved metabolic stability.
• Agrochemical Development: Intermediate in the research and production of advanced crop protection agents and herbicides.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme function.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom chemical synthesis services and scale-up processes.

Basic Information

Product Name	1-Boc-4-(4-Chloro-Benzoyl)-Piperidine
CAS No.	209808-06-0
Molecular Formula	C17H22ClNO3
Molecular Weight	323.82 g/mol
Synonyms	1-Boc-4-(4-Chlorobenzoyl)piperidine; tert-Butyl 4-(4-chlorobenzoyl)piperidine-1-carboxylate; 4-(4-Chlorobenzoyl)piperidine-1-carboxylic Acid tert-Butyl Ester; 1-(tert-Butoxycarbonyl)-4-(4-chlorobenzoyl)piperidine; N-Boc-4-(4-Chlorobenzoyl)piperidine; Piperidine, 1-[(1,1-dimethylethoxy)carbonyl]-4-[(4-chlorophenyl)carbonyl]-; 209808-06-0; 1-Boc-4-(p-Chlorobenzoyl)piperidine
EINECS	Contact for details

Quality Control

Our 1-Boc-4-(4-Chloro-Benzoyl)-Piperidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our clients' regulatory requirements in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.