Description

(R)-1-tert-Butyl 2-Ethyl Piperazine-1,2-Dicarboxylate is a high-purity chiral piperazine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring precise stereochemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where specific stereochemistry is crucial for biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: Employed in medicinal chemistry for the design and synthesis of peptide analogs and conformationally restricted scaffolds.
• Custom Chemical Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs working on proprietary client projects.

Basic Information

Product Name	(R)-1-tert-Butyl 2-Ethyl Piperazine-1,2-Dicarboxylate
CAS No.	209592-05-2
Molecular Formula	C13H24N2O4
Molecular Weight	272.34 g/mol
Synonyms	1-Boc-2-(ethoxycarbonyl)-(R)-piperazine; (R)-1-(tert-Butoxycarbonyl)-2-(ethoxycarbonyl)piperazine; (R)-N-Boc-N'-ethoxycarbonylpiperazine; (R)-Piperazine-1,2-dicarboxylic acid 1-tert-butyl 2-ethyl ester; (2R)-1-[(2-Methylpropan-2-yl)oxycarbonyl]-2-(ethoxycarbonyl)piperazine; (R)-1-tert-Butoxycarbonyl-2-ethoxycarbonylpiperazine; (R)-Boc-Pip-OEt; (R)-1-N-Boc-2-N-ethoxycarbonylpiperazine
EINECS	Contact for details

Quality Control

Our (R)-1-tert-Butyl 2-Ethyl Piperazine-1,2-Dicarboxylate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and cGMP applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.