Description

Pentanoic Acid, 4-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-, (4S)- (9Ci) is a high-purity, chiral non-natural amino acid derivative, specifically the Boc-protected form of (S)-2-aminopentanoic acid. This compound is a critical chiral building block in the synthesis of complex pharmaceutical intermediates and bioactive peptides, where stereochemical integrity is paramount. It is essential for research and production in advanced organic synthesis, medicinal chemistry, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in peptidomimetics and enzyme inhibitors.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis as a protected amino acid building block to introduce specific structural motifs.
• Medicinal Chemistry Research: Serves as a versatile scaffold in drug discovery programs for creating compound libraries and probing structure-activity relationships (SAR).
• Asymmetric Synthesis: Employed as a chiral auxiliary or starting material in stereoselective chemical transformations to construct complex molecules.
• Bioconjugation & Labeling: The carboxylic acid and protected amine functionalities allow for selective conjugation to biomolecules or other chemical entities.
• Agrochemical Research: Potential use in the development of chiral active ingredients for crop protection agents.

Basic Information

Product Name	Pentanoic Acid, 4-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-, (4S)- (9Ci)
CAS No.	207924-92-3
Molecular Formula	C10H19NO4
Molecular Weight	217.26 g/mol
Synonyms	(S)-2-((tert-Butoxycarbonyl)amino)pentanoic acid; Boc-L-norvaline; (S)-2-(Boc-amino)pentanoic acid; Boc-Norvaline-OH; (S)-2-[(tert-Butoxycarbonyl)amino]valeric acid; (4S)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]pentanoic acid; L-Norvaline, N-Boc-; Boc-L-2-Aminopentanoic acid
EINECS	Contact for details

Quality Control

Our Pentanoic Acid, 4-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-, (4S)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.