Description

1,2-Di 3,7,11,15-Tetramethylhexadecanoyl-Sn-Glycero-3-Phosphocholine is a high-purity synthetic phospholipid, specifically a phosphatidylcholine derivative with branched-chain phytanic acid moieties. This compound is critical for advanced research and development in lipid-based drug delivery systems due to its unique structural properties that influence membrane fluidity and stability. It is primarily utilized by pharmaceutical R&D teams, formulation scientists, and academic researchers working on liposomes, lipid nanoparticles (LNPs), and other sophisticated biomimetic membranes.

Application

• Liposome & Lipid Nanoparticle (LNP) Formulation: A key structural lipid for creating stable, targeted drug delivery vehicles for mRNA, siRNA, and small molecule therapeutics.
• Biomembrane & Model Membrane Studies: Used to investigate membrane dynamics, protein-lipid interactions, and the effects of branched-chain fatty acids on bilayer properties.
• Pharmaceutical Excipient Development: Serves as a functional excipient to enhance the solubility, bioavailability, and targeted release of poorly soluble active pharmaceutical ingredients (APIs).
• Diagnostic Reagent Component: Incorporated into reagents and assays for clinical diagnostics and biochemical research that require specific membrane environments.
• Cosmetic & Dermal Formulations: Employed in high-end cosmetic products for its biomimetic and skin-barrier repair properties.

Basic Information

Product Name	1,2-Di 3,7,11,15-Tetramethylhexadecanoyl-Sn-Glycero-3-Phosphocholine
CAS No.	207131-40-6
Molecular Formula	C50H100NO9P
Molecular Weight	890.30 g/mol
Synonyms	1,2-Diphytanoyl-sn-glycero-3-phosphocholine; DPhyPC; 1,2-Di(3,7,11,15-tetramethylhexadecanoyl)-sn-glycero-3-phosphocholine; Phosphatidylcholine, 1,2-di-O-phytanyl-sn-glycero-3-; Diphytanoyl Phosphatidylcholine; PC(16:0/16:0(phytanoyl)); 1,2-Diphytanoyl Phosphatidylcholine; 1,2-Di-O-phytanyl-sn-glycero-3-phosphocholine
EINECS	Contact for details

Quality Control

Our 1,2-Di 3,7,11,15-Tetramethylhexadecanoyl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and MS for identity verification, to ensure it meets the stringent requirements for pharmaceutical and research applications. Certificates of Analysis (COA) with detailed chromatograms and full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white waxy solid or film
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.