Description

1-Piperidinecarbonyl Chloride, 4-Oxo- (9Ci) is a highly reactive acid chloride derivative of 4-piperidone, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to efficiently introduce the 4-oxopiperidine-1-carbonyl moiety, a privileged scaffold found in numerous pharmacologically active compounds. This intermediate is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of piperidine-based drug candidates, including kinase inhibitors, receptor antagonists, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that incorporate the 4-oxopiperidine structure.
• Chemical Biology & Proteomics: Employed as a reactive handle for labeling or modifying biomolecules, facilitating the study of protein function and interaction.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored properties.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex molecules for clients.

Basic Information

Product Name	1-Piperidinecarbonyl Chloride, 4-Oxo- (9Ci)
CAS No.	206182-51-6
Molecular Formula	C7H8ClNO2
Molecular Weight	173.60 g/mol
Synonyms	4-Oxopiperidine-1-carbonyl chloride; 1-(Chlorocarbonyl)-4-piperidinone; 4-Piperidone-1-carbonyl chloride; 4-Oxo-1-piperidinecarbonyl chloride; N-Carboxy-4-piperidone chloride; 1-Piperidinecarbonyl chloride, 4-oxo-; 4-Oxo-piperidine-1-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our production of 1-Piperidinecarbonyl Chloride, 4-Oxo- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.