Description

Piperazinone, 6-(Hydroxymethyl)-, (6R)- (9Ci) is a high-value, chiral piperazinone derivative characterized by its hydroxymethyl functional group. This compound serves as a critical chiral building block and advanced pharmaceutical intermediate, enabling the synthesis of complex, biologically active molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly in areas requiring stereochemical precision.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in neurological and anti-infective drug candidates.
• Organic Synthesis Building Block: Used in asymmetric synthesis and medicinal chemistry for constructing complex heterocyclic scaffolds with defined stereochemistry.
• Biochemical Research: Employed as a standard or reagent in studies investigating enzyme inhibition, receptor binding, and other structure-activity relationship (SAR) studies.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and optimization of synthetic routes for target molecules under Good Manufacturing Practice (GMP) guidelines.

Basic Information

Product Name	Piperazinone, 6-(Hydroxymethyl)-, (6R)- (9Ci)
CAS No.	205993-33-5
Molecular Formula	C5H10N2O2
Molecular Weight	130.15 g/mol
Synonyms	(6R)-6-(Hydroxymethyl)piperazin-2-one; (R)-6-(Hydroxymethyl)piperazin-2-one; 6R-Hydroxymethylpiperazinone; (R)-1,4-Diazinan-2-one, 6-(hydroxymethyl)-; 205993-33-5; (6R)-6-(Hydroxymethyl)-2-piperazinone; Chiral Hydroxymethyl Piperazinone
EINECS	Contact for details

Quality Control

Our Piperazinone, 6-(Hydroxymethyl)-, (6R)- (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.