Description

1-Boc-4-(Piperidin-4-Yl)-Piperazine is a high-purity, protected heterocyclic amine building block of significant importance in modern organic synthesis. Its core value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is primarily needed by medicinal chemists and process development scientists working on new drug candidates, especially in the areas of kinase inhibitors, central nervous system (CNS) agents, and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Scaffold: Used to build diverse compound libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Kinase Inhibitor Synthesis: Serves as a core structural element in the design and synthesis of potential kinase-targeted therapies.
• CNS Drug Discovery: Employed in the construction of molecules targeting neurological and psychiatric disorders.
• Peptidomimetic Chemistry: Utilized to introduce rigid, nitrogen-containing heterocycles into peptide-like structures.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes under cGMP conditions.

Basic Information

Product Name	1-Boc-4-(Piperidin-4-Yl)-Piperazine
CAS No.	205059-24-1
Molecular Formula	C14H27N3O2
Molecular Weight	269.39 g/mol
Synonyms	1-Boc-4-(4-Piperidyl)piperazine; tert-Butyl 4-(piperidin-4-yl)piperazine-1-carboxylate; 4-(1-Piperazinyl)piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(4-piperidinyl)piperazine; N-Boc-4-(4-piperidyl)piperazine; Piperazine, 1-(1,1-dimethylethoxy)carbonyl-4-(4-piperidinyl)-; 205059-24-1
EINECS	Contact for details

Quality Control

Our 1-Boc-4-(Piperidin-4-Yl)-Piperazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by advanced analytical techniques like HPLC, NMR, and mass spectrometry. We support development from milligram to kilogram scale with a commitment to quality that meets the stringent requirements of pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.