Description

1-(2,4-Difluorobenzyl)Piperazine 2Hcl is a high-purity, functionalized piperazine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile, difluorobenzyl-substituted piperazine scaffold essential for constructing complex molecules with tailored properties. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and active ingredient development.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective agents.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Synthesis: Serves as a precursor in the development of new herbicides, fungicides, and pesticides, leveraging the fluorine atoms for enhanced bioactivity and metabolic stability.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for metal catalysis and in the preparation of functional materials.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	1-(2,4-Difluorobenzyl)Piperazine 2Hcl
CAS No.	204013-06-9
Molecular Formula	C11H14F2N2·2HCl
Molecular Weight	299.16 g/mol
Synonyms	1-[(2,4-Difluorophenyl)methyl]piperazine dihydrochloride; 2,4-Difluorobenzylpiperazine Dihydrochloride; N-(2,4-Difluorobenzyl)piperazine Dihydrochloride; Piperazine, 1-[(2,4-difluorophenyl)methyl]-, dihydrochloride; 204013-06-9; 1-(2,4-Difluorobenzyl)piperazine Hydrochloride Salt
EINECS	Contact for details

Quality Control

Our 1-(2,4-Difluorobenzyl)Piperazine 2Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting its use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.