Description

1-Boc-4-Amino-Piperidine-4-Methanol is a high-purity, protected piperidine derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in providing a versatile scaffold with orthogonal protecting groups, enabling the controlled introduction of functional groups for complex molecule construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of protease inhibitors, kinase inhibitors, and other small molecule therapeutics.
• Agrochemical Research: Used in constructing novel pesticide and herbicide candidates with specific stereochemical requirements.
• Peptidomimetics Development: Serves as a constrained, non-natural amino acid analog in the design of peptide-like drug candidates.
• Ligand and Catalyst Synthesis: Employed in the preparation of chiral ligands for asymmetric catalysis and organometallic complexes.
• Chemical Biology Probes: Utilized as a core structure for developing molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring a functionalized, protected piperidine core.

Basic Information

Product Name	1-Boc-4-Amino-Piperidine-4-Methanol
CAS No.	203186-96-3
Molecular Formula	C12H24N2O3
Molecular Weight	244.33 g/mol
Synonyms	4-(Aminomethyl)-1-Boc-4-piperidinol; tert-Butyl 4-(aminomethyl)-4-hydroxypiperidine-1-carboxylate; 4-(Hydroxymethyl)-1-Boc-4-aminopiperidine; 1-Boc-4-(aminomethyl)piperidin-4-ol; 1-N-Boc-4-amino-4-(hydroxymethyl)piperidine; 4-Amino-4-(hydroxymethyl)piperidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-amino-4-(hydroxymethyl)piperidine
EINECS	Contact for details

Quality Control

Our 1-Boc-4-Amino-Piperidine-4-Methanol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical R&D and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.