Description

1-(3-Nitrobenzyl)-Piperazine is a versatile nitro-aromatic piperazine derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and a valuable building block for the development of novel chemical entities. It is primarily utilized by research institutions and fine chemical manufacturers engaged in medicinal chemistry, agrochemical research, and material science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in drug discovery and lead optimization programs.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for catalysis and metal complexation.
• Material Science: Intermediate in the synthesis of polymers, dyes, and other functional materials requiring nitro-aromatic functionalities.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Item	Details
Product Name	1-(3-Nitrobenzyl)-Piperazine
CAS No.	203047-37-4
Molecular Formula	C11H15N3O2
Molecular Weight	221.26 g/mol
Synonyms	1-[(3-Nitrophenyl)methyl]piperazine; 3-Nitrobenzylpiperazine; N-(3-Nitrobenzyl)piperazine; Piperazine, 1-[(3-nitrophenyl)methyl]-; 1-(3-Nitro-benzyl)-piperazine; 203047-37-4; 1-(3-Nitrobenzyl)piperazine
EINECS	Contact for details

Quality Control

Our 1-(3-Nitrobenzyl)-Piperazine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all relevant specifications. We can support development projects requiring compliance with ICH guidelines for impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. For long-term storage, consider using an inert atmosphere to mitigate potential oxidation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.