Description

tert-Butyl 4-(3-Cyanobenzyl)Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a piperazine core with a cyano-substituted benzyl group. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs), particularly in the areas of central nervous system (CNS) and oncology therapeutics.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• CNS Drug Development: Used in the research and production of potential therapeutics targeting neurological disorders.
• Oncology Research: Employed as a building block for compounds being investigated for anti-cancer properties.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations for custom synthesis projects.
• Process Chemistry & Scale-Up: Integral in developing and scaling robust synthetic routes from laboratory to pilot and commercial production.

Basic Information

Product Name	tert-Butyl 4-(3-Cyanobenzyl)Piperazine-1-Carboxylate
CAS No.	203047-35-2
Molecular Formula	C17H23N3O2
Molecular Weight	301.39 g/mol
Synonyms	1-Boc-4-(3-Cyanobenzyl)piperazine; 4-(3-Cyanobenzyl)piperazine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-[(3-cyanophenyl)methyl]piperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(3-cyanobenzyl)piperazine; BOC-4-(3-Cyanobenzyl)piperazine; N-Boc-4-(3-cyanobenzyl)piperazine; Piperazine, 4-[(3-cyanophenyl)methyl]-, 1-(1,1-dimethylethyl) ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(3-Cyanobenzyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding pharmaceutical R&D and production. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to ICH guidelines for stability and impurity characterization, supporting regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Related Substances (HPLC)	Any individual impurity ≤0.5%
Total Impurities	≤2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.