Description

tert-Butyl 4-(3-Fluorobenzyl)Piperazine-1-Carboxylate is a high-purity, protected piperazine derivative serving as a critical building block in advanced organic synthesis. This compound is essential for medicinal chemistry research and development, particularly in the construction of novel pharmacologically active molecules. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers for creating potential drug candidates targeting central nervous system and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug molecules, especially those containing a piperazine scaffold.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns for constructing and diversifying compound libraries.
• API Development: Serves as a precursor in the development of Active Pharmaceutical Ingredients (APIs) for preclinical and clinical studies.
• Protecting Group Strategy: The tert-butoxycarbonyl (Boc) group provides a versatile protecting group for the piperazine nitrogen, enabling selective synthetic transformations.
• Ligand Synthesis: Employed in the preparation of ligands for biological target evaluation and biochemical assays.

Basic Information

Product Name	tert-Butyl 4-(3-Fluorobenzyl)Piperazine-1-Carboxylate
CAS No.	203047-34-1
Molecular Formula	C16H23FN2O2
Molecular Weight	294.37 g/mol
Synonyms	1-Boc-4-(3-Fluorobenzyl)piperazine; 1-(tert-Butoxycarbonyl)-4-(3-fluorobenzyl)piperazine; tert-Butyl 4-[(3-fluorophenyl)methyl]piperazine-1-carboxylate; 4-(3-Fluorobenzyl)piperazine-1-carboxylic acid tert-butyl ester; 203047-34-1; 1-N-Boc-4-(3-fluorobenzyl)piperazine; BOC-4-(3-Fluorobenzyl)piperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(3-Fluorobenzyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to industry best practices, and specifications can be aligned with customer requirements for advanced pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.