Description

tert-Butyl 4-(3-Nitrobenzyl)Piperazine-1-Carboxylate is a high-purity, protected piperazine derivative serving as a critical building block in advanced organic synthesis. This compound is essential for medicinal chemistry research and pharmaceutical development, offering a versatile scaffold for constructing complex molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Peptidomimetic Synthesis: Employed in the construction of peptidomimetics and other bioactive molecules that incorporate a piperazine moiety.
• Agrochemical Development: Serves as an intermediate in the research and synthesis of novel crop protection agents and pesticides.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized fine chemicals.
• Chemical Biology Probes: Used in the development of chemical probes for studying biological pathways and protein function.

Basic Information

Product Name	tert-Butyl 4-(3-Nitrobenzyl)Piperazine-1-Carboxylate
CAS No.	203047-33-0
Molecular Formula	C16H23N3O4
Molecular Weight	321.37 g/mol
Synonyms	1-Boc-4-(3-nitrobenzyl)piperazine; tert-Butyl 4-[(3-nitrophenyl)methyl]piperazine-1-carboxylate; 4-(3-Nitrobenzyl)piperazine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(3-nitrobenzyl)piperazine; Boc-4-(3-nitrobenzyl)piperazine; 203047-33-0; Piperazine, 4-[(3-nitrophenyl)methyl]-, 1-(1,1-dimethylethyl) ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(3-Nitrobenzyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support development and commercial projects requiring material that meets ICH guidelines for impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.