Description

Etoricoxib is a highly selective COX-2 inhibitor belonging to the class of nonsteroidal anti-inflammatory drugs (NSAIDs). This active pharmaceutical ingredient (API) is valued for its potent anti-inflammatory and analgesic properties with a favorable gastrointestinal safety profile. It is primarily utilized by pharmaceutical manufacturers in the research, development, and commercial production of prescription medications for the management of acute and chronic pain, osteoarthritis, and rheumatoid arthritis.

Application

• Pharmaceutical API: Core ingredient in the formulation of prescription tablets for pain and inflammation management.
• Analgesic Drug Development: Used in R&D for new analgesic formulations targeting COX-2 enzyme inhibition.
• Anti-inflammatory Medications: Manufacture of drugs for conditions like osteoarthritis, rheumatoid arthritis, and gouty arthritis.
• Clinical Research: Serves as a reference standard and raw material in preclinical and clinical studies.
• Generic Drug Production: Sourcing for manufacturers producing bioequivalent versions of branded etoricoxib drugs.
• Veterinary Pharmaceutical Research: Potential application in developing anti-inflammatory treatments for animal health.

Basic Information

Product Name	Etoricoxib
CAS No.	202409-33-4
Molecular Formula	C18H15ClN2O2S
Molecular Weight	358.84 g/mol
Synonyms	5-Chloro-6'-methyl-3-[4-(methylsulfonyl)phenyl]-2,3'-bipyridine; MK-0663; Arcoxia; Algix; Tauxib; Coxib; Loxoprofen (related class); Selective COX-2 Inhibitor
EINECS	Contact for details

Quality Control

Our Etoricoxib is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles to support our global clientele in regulated markets.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Solubility	Practically insoluble in water; soluble in dimethylformamide, slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.