Description

5-(Piperazin-1-Yl)Pyrimidine CAS NO 202135-70-4 is a high-purity, versatile heterocyclic building block featuring a pyrimidine core linked to a piperazine moiety. This compound is of significant commercial importance as a key intermediate in the synthesis of complex pharmaceutical molecules, particularly those targeting central nervous system (CNS) disorders and various kinase pathways. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of drug candidates, especially for CNS-targeted therapies, kinase inhibitors, and antiviral agents.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Chemical Synthesis Building Block: Serves as a versatile scaffold for constructing more complex heterocyclic compounds in medicinal and combinatorial chemistry.
• Biochemical Research: Employed as a ligand or probe in biochemical assays to study enzyme interactions and receptor binding.
• Material Science Precursor: Potential use in the synthesis of organic semiconductors or metal-organic frameworks (MOFs) due to its nitrogen-rich, chelating structure.

Basic Information

Product Name	5-(Piperazin-1-Yl)Pyrimidine
CAS No.	202135-70-4
Molecular Formula	C8H12N4
Molecular Weight	164.21 g/mol
Synonyms	5-(1-Piperazinyl)pyrimidine; 5-Piperazin-1-ylpyrimidine; Pyrimidine, 5-(1-piperazinyl)-; 5-Pyrimidinylpiperazine; 1-(Pyrimidin-5-yl)piperazine; 5-(Piperazin-1-yl)pyrimidine; 202135-70-4; 5-Piperazinopyrimidine
EINECS	Contact for details

Quality Control

Our 5-(Piperazin-1-Yl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.