Description

1-Palmitoyl-2-Oleoyl-Sn-Glycero-3-Phosphoglycerol, Sodium Salt is a high-purity, synthetic phospholipid, specifically a sodium salt of phosphatidylglycerol (POPG). This compound is a critical component for creating biomimetic membranes and is essential for advanced research and formulation development in life sciences. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and cosmetic industries for applications requiring precise membrane modeling and delivery systems.

Application

• Liposome and Lipid Nanoparticle (LNP) Formulation: A key excipient for constructing stable, uniform vesicles for drug and vaccine delivery, including mRNA-based therapeutics.
• Biomembrane Research: Used to create model membranes (e.g., liposomes, supported lipid bilayers) for studying membrane protein interactions, permeability, and fusion processes.
• Pulmonary Surfactant Mimetics: Investigated as a component in synthetic lung surfactant formulations for respiratory distress syndrome research.
• Cosmetic Actives Carrier: Employed in advanced cosmetic formulations to enhance the skin penetration and stability of active ingredients.
• Diagnostic Assay Development: Serves as a coating or capture agent in diagnostic platforms and biosensors that rely on membrane-bound interactions.
• Cell Culture & Cryopreservation: Used as an additive to improve cell membrane integrity and viability in specialized cell culture media and cryoprotectant solutions.

Basic Information

Product Name	1-Palmitoyl-2-Oleoyl-sn-Glycero-3-Phosphoglycerol, Sodium Salt
CAS No.	202070-86-8
Molecular Formula	C41H78NaO10P
Molecular Weight	785.01 g/mol
Synonyms	POPG, Sodium Salt; 1-Palmitoyl-2-oleoyl-phosphatidylglycerol; POPG-Na; (16:0-18:1) PG; PG(16:0/18:1); Phosphatidylglycerol (16:0/18:1); 1-Hexadecanoyl-2-(9Z-octadecenoyl)-sn-glycero-3-phospho-(1'-rac-glycerol) sodium salt; 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoglycerol sodium salt
EINECS	Contact for details

Quality Control

Our 1-Palmitoyl-2-Oleoyl-Sn-Glycero-3-Phosphoglycerol, Sodium Salt is manufactured under strict quality systems. Each batch is characterized using advanced analytical techniques to ensure identity, purity, and consistency suitable for research and formulation. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay, fatty acid profile, and impurity limits. Our quality commitment supports applications requiring GMP-grade materials and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen). The product is hygroscopic (moisture-sensitive) and easily oxidized; allow the sealed vial to equilibrate to room temperature before opening to minimize condensation. Once opened, use immediately or re-purge the container with inert gas and reseal tightly.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Fatty Acid Composition (GC)	Palmitic acid (C16:0): 45-55% Oleic acid (C18:1): 45-55%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Peroxide Value	≤ 5.0 meq/kg
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.