Description

Fmoc-Orn(Pyrazinylcarbonyl)-Oh is a specialized, protected amino acid derivative designed for advanced solid-phase peptide synthesis (SPPS). This compound is critical for researchers and manufacturers requiring precise, high-purity building blocks to construct complex peptides with specific functional modifications. It is primarily utilized in pharmaceutical R&D, biotechnology, and academic laboratories for the development of novel therapeutic peptides, diagnostic agents, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a key Fmoc-protected building block for the controlled incorporation of ornithine with a pyrazinylcarbonyl side-chain modification into peptide sequences.
• Pharmaceutical Research: Used in the discovery and development of novel peptide-based drugs, including targeted therapies and hormone analogs.
• Bioconjugation: Facilitates the site-specific modification of peptides and proteins for creating antibody-drug conjugates (ADCs) or diagnostic imaging agents.
• Chemical Biology: Employed in the synthesis of peptide libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Material Science: Can be used to create functionalized peptide-based biomaterials and hydrogels with tailored properties.

Basic Information

Product Name	Fmoc-Orn(Pyrazinylcarbonyl)-Oh
CAS No.	201046-61-9
Molecular Formula	C26H24N4O5
Molecular Weight	472.50 g/mol
Synonyms	Fmoc-Orn(Pyrazinylcarbonyl)-OH; N-α-Fmoc-N-δ-(pyrazine-2-carbonyl)-L-ornithine; Fmoc-L-Orn(Pyrazinylcarbonyl)-OH; Fmoc-Orn(Pz)-OH; 9-Fluorenylmethyloxycarbonyl-Orn(Pyrazinylcarbonyl)-OH; Nδ-(Pyrazine-2-carbonyl)-Nα-(9-fluorenylmethoxycarbonyl)-L-ornithine; Fmoc-Orn(Pyrazine-2-carbonyl)-OH; (2S)-5-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-[(pyrazine-2-carbonyl)amino]pentanoic acid
EINECS	Contact for details

Quality Control

Our Fmoc-Orn(Pyrazinylcarbonyl)-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive research and production applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines for the production of pharmaceutical intermediates, ensuring traceability and documentation for regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.