Description

Nicotine Salicylate is a pharmaceutical-grade salt formed from nicotine and salicylic acid, offering enhanced stability and specific solubility characteristics for advanced formulations. This compound is critical for researchers and manufacturers requiring a precisely defined nicotine derivative for controlled delivery systems and analytical standards. It is primarily utilized in the pharmaceutical and life science sectors for the development of reference materials, smoking cessation aids, and in biochemical research.

Application

• Pharmaceutical Reference Standard: Serves as a certified standard for quality control and analytical method development in pharmacopeial testing.
• Smoking Cessation Research: Used in preclinical and clinical studies to investigate nicotine pharmacokinetics and the efficacy of nicotine replacement therapies (NRTs).
• Biochemical Reagent: Employed in laboratory research to study nicotinic acetylcholine receptor (nAChR) interactions and related neurological pathways.
• Controlled-Release Formulations: A key ingredient in the development of advanced transdermal patches, lozenges, or other delivery mechanisms due to its salt properties.
• Analytical Chemistry: Used as a calibration standard in High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) for accurate quantification of nicotine derivatives.

Basic Information

Product Name	Nicotine Salicylate
CAS No.	29790-52-1
Molecular Formula	C17H20N2O3
Molecular Weight	300.36 g/mol
Synonyms	Nicotine Salicylate; Nicotine Salicylate Salt; 3-[(2S)-1-Methylpyrrolidin-2-yl]pyridine salicylate; Salicylic Acid Nicotine Salt; Nicotine Salicylate (1:1); Nicotine Monosalicylate; Nicotine Hydrogen Salicylate; Pyridine, 3-[(2S)-1-methyl-2-pyrrolidinyl]-, (2S)-, salicylate (1:1)
EINECS	Contact for details

Quality Control

Our Nicotine Salicylate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identification, assay, and impurity profiling, to ensure it meets stringent specifications for pharmaceutical research and development. A Certificate of Analysis (COA) detailing purity, residual solvents, and heavy metals is provided with every shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.