Description

4-Dimethylamino-1-Naphthyl Isothiocyanate is a specialized organic compound featuring a reactive isothiocyanate group attached to a dimethylamino-substituted naphthalene core. This unique structure makes it a valuable building block and derivatization reagent for synthesizing complex molecules and functional materials. It is primarily utilized by research institutions, pharmaceutical developers, and specialty chemical manufacturers engaged in advanced organic synthesis and analytical chemistry.

Application

• Fluorescent Labeling Reagent: Used for the derivatization and detection of amines, amino acids, and peptides in high-performance liquid chromatography (HPLC) and capillary electrophoresis for enhanced sensitivity.
• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel drug candidates, particularly those targeting specific biological pathways.
• Polymer Chemistry: Acts as a functional monomer or cross-linking agent in the synthesis of specialty polymers with tailored optical or chemical properties.
• Bioconjugation: Employed for coupling biomolecules (e.g., proteins, antibodies) to other entities via its reactive isothiocyanate group, which readily forms thiourea bonds with primary amines.
• Chemical Research: A versatile reagent in academic and industrial laboratories for synthesizing heterocyclic compounds, dyes, and sensors.
• Material Science: Used in the development of advanced organic materials, including organic light-emitting diodes (OLEDs) and nonlinear optical materials.

Basic Information

Product Name	4-Dimethylamino-1-Naphthyl Isothiocyanate
CAS No.	29711-79-3
Molecular Formula	C₁₃H₁₂N₂S
Molecular Weight	228.31 g/mol
Synonyms	1-Isothiocyanato-4-(dimethylamino)naphthalene; 4-(Dimethylamino)-1-naphthyl isothiocyanate; 4-(Dimethylamino)naphthalene-1-isothiocyanate; Dansyl isothiocyanate analog; DMI; DMN-ITC; 1-Dimethylaminonaphthalene-5-isothiocyanate
EINECS	Contact for details

Quality Control

Our 4-Dimethylamino-1-Naphthyl Isothiocyanate is produced under stringent conditions to ensure high purity and batch-to-batch consistency. Quality is verified through a comprehensive suite of analytical techniques including HPLC, NMR, and FT-IR. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.