Description

Phenylthiohydantoin-Threonine is a specialized derivative of threonine, a crucial amino acid, modified with a phenylthiohydantoin group. This compound is of significant value in advanced biochemical research and analytical chemistry, particularly for peptide sequencing and protein structure analysis. It is primarily utilized by research institutions, pharmaceutical R&D departments, and analytical laboratories involved in proteomics and amino acid chemistry.

Application

• Peptide Sequencing: Acts as a key intermediate or reference standard in the Edman degradation process for determining the amino acid sequence of peptides and proteins.
• Analytical Reference Standard: Serves as a high-purity calibrant in High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) for the identification and quantification of amino acid derivatives.
• Biochemical Research: Used in studies investigating protein folding, post-translational modifications, and enzyme-substrate interactions where modified amino acids are required.
• Pharmaceutical Development: Employed in the synthesis and quality control of peptide-based drugs and novel therapeutic agents.
• Proteomics: A valuable tool in large-scale protein analysis workflows for characterizing complex biological samples.

Basic Information

Product Name	Phenylthiohydantoin-Threonine
CAS No.	29583-08-2
Molecular Formula	C₁₃H₁₄N₂O₃S
Molecular Weight	278.33 g/mol
Synonyms	PTH-Threonine; 3-[(Phenylamino)(thioxo)methyl]-2-amino-4-hydroxybutanoic acid; 2-Amino-3-[(phenylcarbamothioyl)amino]-4-hydroxybutanoic acid; Threonine phenylthiohydantoin; PTH-Thr; Edman degradation product of Threonine; (2S,3R)-2-Amino-3-[(phenylcarbamothioyl)amino]-4-hydroxybutanoic acid
EINECS	Contact for details

Quality Control

Our Phenylthiohydantoin-Threonine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed batch-specific data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.