Description

18,19-Dihydrogelsemine is a specialized alkaloid derivative of significant interest in advanced chemical synthesis and research. This compound serves as a critical intermediate and reference standard for developing novel bioactive molecules and studying complex natural product pathways. It is primarily utilized by research institutions and pharmaceutical development teams focused on neuropharmacology and analytical chemistry. The high-purity material is essential for ensuring the accuracy and reproducibility of experimental results in these demanding fields.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the qualitative and quantitative analysis of Gelsemium alkaloids and related compounds in drug development and quality control laboratories.
• Biochemical Research: Employed as a key intermediate or probe in neuroscience and pharmacology research to investigate structure-activity relationships and biological pathways.
• Organic Synthesis: Serves as a sophisticated building block for the semi-synthesis of complex natural product analogs and novel chemical entities with potential therapeutic value.
• Analytical Method Development: Utilized as a standard for developing and validating chromatographic methods (HPLC, LC-MS) for the detection and quantification of alkaloids in various matrices.

Basic Information

Item	Detail
Product Name	18,19-Dihydrogelsemine
CAS No.	29576-86-1
Molecular Formula	C20H24N2O3
Molecular Weight	340.42 g/mol
Synonyms	Dihydrogelsemine; 18,19-Dihydrogelsemin; (19R)-18,19-Dihydrogelsemine; Gelsemine, 18,19-dihydro-; 18,19-Dihydro-gelsemine; 18,19-Dihydrogelsemin [German]; 18,19-Dihydrogelsemine [French]
EINECS	Contact for details

Quality Control

Our 18,19-Dihydrogelsemine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each lot is accompanied by comprehensive analytical documentation. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.