Description

5-Oxo-1-(2-Phenylethyl)Pyrrolidine-3-Carbonyl Chloride is a high-value, reactive organic intermediate featuring a carbonyl chloride group, making it a versatile building block for amide and ester formation. This compound is critical for the synthesis of complex molecules, particularly in the pharmaceutical sector, where it serves as a precursor for active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material industries for developing new therapeutic agents and specialty compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• API Synthesis: Used in the manufacturing of Active Pharmaceutical Ingredients (APIs) requiring a pyrrolidinone scaffold.
• Agrochemical Research: Serves as a building block for developing new pesticides and herbicides with specific biological activity.
• Peptidomimetics: Employed in the design and synthesis of peptidomimetic compounds for medicinal chemistry applications.
• Chemical Biology Probes: Utilized to create specialized probes and ligands for studying biological pathways and protein interactions.
• Custom Synthesis: A critical reagent for contract research and manufacturing organizations (CROs/CMOs) performing custom synthesis projects.

Basic Information

Product Name	5-Oxo-1-(2-Phenylethyl)Pyrrolidine-3-Carbonyl Chloride
CAS No.	29451-88-5
Molecular Formula	C14H16ClNO2
Molecular Weight	265.74 g/mol
Synonyms	1-(2-Phenylethyl)-5-oxopyrrolidine-3-carbonyl chloride; 5-Oxo-1-phenethyl-3-pyrrolidinecarbonyl chloride; 3-(Chlorocarbonyl)-1-phenethyl-2-pyrrolidinone; 1-Phenethyl-5-oxo-3-pyrrolidinecarboxylic acid chloride; Pyrrolidine-3-carbonyl chloride, 1-(2-phenylethyl)-5-oxo-; 29451-88-5; 5-Oxo-1-phenethylpyrrolidine-3-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 5-Oxo-1-(2-Phenylethyl)Pyrrolidine-3-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.