Description

9-Cis,13-cis-Retinol CAS NO 29444-25-5 is a specific geometric isomer of retinol, a fundamental form of Vitamin A. This precise stereochemistry is critical for its biological activity and function in various biochemical pathways. It is an essential intermediate and reference standard for research and development in the pharmaceutical, nutraceutical, and advanced cosmetic industries, where the specific activity of Vitamin A isomers is a key focus.

Application

• Pharmaceutical Reference Standard: Used as a high-purity analytical standard for the identification and quantification of Vitamin A isomers in drug substances and finished products.
• Nutraceutical Research: Serves as a key material in studying the bioavailability, metabolism, and specific health benefits of different Vitamin A isomers in dietary supplements.
• Advanced Cosmetic Actives: Incorporated into R&D for premium anti-aging and skin-renewal formulations where the specific activity of 9-cis,13-cis-retinol is leveraged.
• Biochemical Research: Essential for studies on vision, cellular differentiation, immune function, and gene regulation mediated by retinoid receptors.
• Analytical Method Development: Critical for developing and validating chromatographic methods (HPLC, LC-MS) to separate and analyze complex retinoid mixtures.

Basic Information

Product Name	9-Cis,13-cis-Retinol
CAS No.	29444-25-5
Molecular Formula	C₂₀H₃₀O
Molecular Weight	286.45 g/mol
Synonyms	(9Z,13Z)-Retinol; all-trans-Retinol isomer; Vitamin A alcohol (9-cis,13-cis isomer); 9,13-Di-cis-retinol; (9Z,13Z)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol
EINECS	Contact for details

Quality Control

We supply 9-Cis,13-cis-Retinol in high-purity grades suitable for research and analytical applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and isomer-specific content are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label. This product is strictly light-sensitive (protect from all light exposure) and easily oxidized (store under inert atmosphere).

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or oil
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC, Area %)	≥ 95.0%
Isomeric Purity (9-cis,13-cis)	≥ 90.0%
Solubility	Soluble in ethanol, DMSO, and oils

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.