Description

4-Fluoro-7-Nitrobenzofurazan is a specialized heterocyclic compound that serves as a highly reactive derivatization reagent. Its core value lies in its ability to act as a sensitive fluorogenic and chromogenic label for the detection and quantification of amines, thiols, and other nucleophiles in analytical chemistry. This product is essential for researchers and quality control laboratories in the pharmaceutical, biotechnology, and chemical synthesis sectors who require precise analytical tools for trace analysis and method development.

Application

• Derivatization Agent for HPLC/LC-MS: Used to tag primary and secondary amines, amino acids, and peptides to enhance their detection sensitivity (fluorescence/UV) in liquid chromatography.
• Fluorescent Labeling in Biochemistry: Employed for labeling proteins, antibodies, and other biomolecules to study their structure, function, and interactions.
• Detection of Thiol Groups: Acts as a selective probe for the quantification of cysteine residues and other sulfhydryl-containing compounds in various matrices.
• Research Chemical in Organic Synthesis: Serves as a key building block or intermediate in the synthesis of more complex benzofurazan-based dyes and sensors.
• Analytical Method Development: Utilized in developing new analytical protocols for environmental monitoring, food safety, and pharmaceutical impurity profiling.

Basic Information

Product Name	4-Fluoro-7-Nitrobenzofurazan
CAS No.	29270-56-2
Molecular Formula	C₆H₂FN₃O₃
Molecular Weight	183.10 g/mol
Synonyms	4-Fluoro-7-nitro-2,1,3-benzoxadiazole; NBD-F; 4-Fluoro-7-nitrobenzoxadiazole; 4-Fluoro-7-nitro-2,1,3-benzoxadiazole; 7-Nitro-4-fluorobenzofurazan; 4-Fluoro-7-nitrobenzo-2-oxa-1,3-diazole; 29270-56-2; NBD Fluoride
EINECS	Contact for details

Quality Control

Our 4-Fluoro-7-Nitrobenzofurazan is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and analytical applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizers. Due to its light-sensitive nature, handling should be minimized under direct light.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.