Description

Diethyl 2-(4-Methylpiperazin-1-yl)propanedioate is a high-purity chemical intermediate featuring a malonate ester core substituted with a 4-methylpiperazine moiety. This compound matters as a versatile building block for synthesizing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by fine chemical manufacturers and R&D laboratories working on active pharmaceutical ingredients (APIs), agrochemicals, and specialty organic compounds. Its specific structure makes it valuable for constructing nitrogen-containing heterocycles and other pharmacologically relevant scaffolds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific nitrogen heterocycles.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and complex organic molecules in specialty chemical manufacturing.
• Research & Development: Essential reagent in academic and industrial R&D for exploring new chemical entities and reaction methodologies.
• Ligand and Catalyst Preparation: Utilized in the synthesis of specialized ligands for metal catalysis and coordination chemistry.

Basic Information

Product Name	Diethyl 2-(4-Methylpiperazin-1-yl)propanedioate
CAS No.	28920-63-0
Molecular Formula	C12H22N2O4
Molecular Weight	258.32 g/mol
Synonyms	Diethyl (4-methylpiperazin-1-yl)malonate; 1-(1,3-Diethoxy-1,3-dioxopropan-2-yl)-4-methylpiperazine; Propanedioic acid, 2-(4-methyl-1-piperazinyl)-, diethyl ester; 2-(4-Methylpiperazin-1-yl)malonic acid diethyl ester; Diethyl 2-(4-methyl-1-piperazinyl)malonate; 28920-63-0; 4-Methyl-1-piperazinepropanedioic acid diethyl ester
EINECS	Contact for details

Quality Control

Our Diethyl 2-(4-Methylpiperazin-1-yl)propanedioate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for research and synthesis applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.