Description

[5-[(Dibutylamino)Methyl]-1,2,5-Trimethyl-4-Phenyl-4-Piperidyl] Propanoate Dihydrochloride is a high-purity, complex organic salt primarily utilized as a critical pharmaceutical intermediate. Its value lies in its role as a key building block for the synthesis of specialized active pharmaceutical ingredients (APIs), particularly those targeting neurological pathways. This compound is essential for research and development laboratories, fine chemical manufacturers, and pharmaceutical companies engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) targeted drugs.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new chemical entities.
• Fine Chemical Synthesis: Serves as a specialized building block for creating complex molecules in custom synthesis and contract manufacturing.
• Neurological Agent Development: Particularly relevant in the research of compounds with potential analgesic or neuro-modulatory properties due to its structural features.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.
• Academic Research: Used in university and institutional labs for advanced organic synthesis and pharmacological studies.

Basic Information

Product Name	[5-[(Dibutylamino)Methyl]-1,2,5-Trimethyl-4-Phenyl-4-Piperidyl] Propanoate Dihydrochloride
CAS No.	28867-18-7
Molecular Formula	C28H49Cl2N2O2
Molecular Weight	501.61 g/mol
Synonyms	1,2,5-Trimethyl-4-phenyl-4-piperidinol propanoate (ester), 5-[(dibutylamino)methyl]-, dihydrochloride; Propanoic acid, 1,2,5-trimethyl-4-phenyl-4-piperidinyl ester, 5-[(dibutylamino)methyl]-, dihydrochloride; Loperamide Impurity D (Dihydrochloride); Loperamide Related Compound D; 4-Phenyl-4-piperidinol derivative dihydrochloride; 5-(Dibutylaminomethyl)-1,2,5-trimethyl-4-phenyl-4-piperidinol propionate dihydrochloride
EINECS	Contact for details

Quality Control

Our [5-[(Dibutylamino)Methyl]-1,2,5-Trimethyl-4-Phenyl-4-Piperidyl] Propanoate Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We can supply material compliant with various pharmacopeial standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.