Description

1,4-Ditosyl-1,4-Diazepan-6-Ol is a specialized heterocyclic building block featuring a diazepane core protected by tosyl groups. This compound is valued for its role as a key synthetic intermediate in the development of complex organic molecules, particularly in pharmaceutical research. It is primarily sought by R&D chemists and process development scientists working in medicinal chemistry and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those containing modified diazepane or piperazine scaffolds.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns for constructing diverse compound libraries targeting central nervous system (CNS) and other therapeutic areas.
• Process Chemistry Development: Serves as a standardized building block for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions for clinical trial material production.
• Ligand and Catalyst Synthesis: Employed in the preparation of complex chelating ligands or organocatalysts for asymmetric synthesis.
• Academic Research: Utilized in universities and research institutes for methodological studies in heterocyclic and protective group chemistry.

Basic Information

Product Name	1,4-Ditosyl-1,4-Diazepan-6-Ol
CAS No.	28860-33-5
Molecular Formula	C20H26N2O5S2
Molecular Weight	438.56 g/mol
Synonyms	1,4-Bis(4-methylphenylsulfonyl)-1,4-diazepan-6-ol; 6-Hydroxy-1,4-ditosyl-1,4-diazepane; 1,4-Di-p-toluenesulfonyl-1,4-diazepan-6-ol; 1,4-Di-p-tosyl-1,4-diazepan-6-ol; 1,4-Di(4-toluenesulfonyl)-1,4-diazepan-6-ol; 1,4-Di(tosyl)-1,4-diazepan-6-ol; 1,4-Diazepan-6-ol, 1,4-bis(4-methylbenzenesulfonyl)-
EINECS	Contact for details

Quality Control

Our 1,4-Ditosyl-1,4-Diazepan-6-Ol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for research and development applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.