Description

2-Piperazinemethanol is a versatile heterocyclic building block and chiral intermediate of significant importance in advanced organic synthesis. Its bifunctional structure, containing both a piperazine ring and a hydroxymethyl group, makes it a valuable precursor for constructing complex molecules with tailored properties. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of various drug candidates, particularly those targeting the central nervous system (CNS) and as building blocks for protease inhibitors.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where the piperazine moiety can contribute to biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for creating chelating ligands used in asymmetric catalysis and metal complexation.
• Polymer Modification: Employed to introduce functional amine and alcohol groups into polymer chains, enhancing properties like adhesion, cross-linking, or biocompatibility.
• Chemical Research & Development: A valuable tool for medicinal and process chemists in exploring new synthetic routes and creating compound libraries for screening.

Basic Information

Product Name	2-Piperazinemethanol
CAS No.	28795-50-8
Molecular Formula	C5H12N2O
Molecular Weight	116.16 g/mol
Synonyms	Piperazin-2-ylmethanol; 2-(Hydroxymethyl)piperazine; 2-Piperazinylmethanol; 1-Piperazineethanol (tautomer); α-Piperazinymethanol; (Piperazin-2-yl)methanol; 2-Piperazinmethanol
EINECS	Contact for details

Quality Control

Our 2-Piperazinemethanol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided to guarantee traceability and consistency. We support custom purity grades, including research and pharmaceutical intermediate specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.