Description

8-Methyl-3-(3,4,5-Trimethoxybenzoyl)-2,3,3a,4,5,6-hexahydro-1H-pyrazino[3,2,1-jk]carbazole is a complex heterocyclic organic compound featuring a fused carbazole and pyrazine core structure, functionalized with a trimethoxybenzoyl group. This compound is of significant interest as a key synthetic intermediate in advanced pharmaceutical research and development. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents, particularly those targeting central nervous system disorders.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of potential drug candidates, especially in medicinal chemistry programs.
• Neurological Research: Used in the development and study of compounds targeting specific receptors or enzymes within the central nervous system.
• Chemical Biology Probe: Acts as a scaffold or precursor for creating molecular probes to study biological pathways and protein interactions.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale for new active pharmaceutical ingredients (APIs).
• Academic Research: Utilized in university and institutional labs for synthetic methodology development and exploring new chemical spaces in heterocyclic chemistry.
• Reference Standard: Supplied as a high-purity compound for analytical method development, validation, and quality control in related API manufacturing.

Basic Information

Product Name	8-Methyl-3-(3,4,5-Trimethoxybenzoyl)-2,3,3a,4,5,6-hexahydro-1H-pyrazino[3,2,1-jk]carbazole
CAS No.	28742-53-2
Molecular Formula	C27H30N2O4
Molecular Weight	446.54 g/mol
Synonyms	8-Methyl-3-(3,4,5-trimethoxybenzoyl)-1,2,3,3a,4,5-hexahydropyrazino[3,2,1-jk]carbazole; 1H-Pyrazino[3,2,1-jk]carbazole, 2,3,3a,4,5,6-hexahydro-8-methyl-3-(3,4,5-trimethoxybenzoyl)-; 28742-53-2; Pyrazinocarbazole derivative; Trimethoxybenzoyl hexahydropyrazinocarbazole
EINECS	Contact for details

Quality Control

Our 8-Methyl-3-(3,4,5-Trimethoxybenzoyl)-2,3,3a,4,5,6-hexahydro-1H-pyrazino[3,2,1-jk]carbazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and development use. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.