Description

2-Chloro-1-(8-Methyl-1,2,3A,4,5,6-Hexahydro-Pyrazino[3,2,1-Jk]Carbazol-3-Yl)-Ethanone is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel therapeutic agents. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of central nervous system (CNS) and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, particularly those targeting neurological pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new pharmacophores with enhanced efficacy and selectivity.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core scaffold in the development of potential APIs for treating various CNS disorders.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	2-Chloro-1-(8-Methyl-1,2,3A,4,5,6-Hexahydro-Pyrazino[3,2,1-Jk]Carbazol-3-Yl)-Ethanone
CAS No.	28742-49-6
Molecular Formula	C17H19ClN2O
Molecular Weight	302.80 g/mol
Synonyms	2-Chloro-1-(8-methyl-1,2,3a,4,5,6-hexahydropyrazino[3,2,1-jk]carbazol-3-yl)ethanone; 2-Chloro-1-(8-methyl-1,2,3a,4,5,6-hexahydro-3H-pyrazino[3,2,1-jk]carbazol-3-yl)ethan-1-one; 28742-49-6; Ethanone, 2-chloro-1-(8-methyl-1,2,3a,4,5,6-hexahydro-3H-pyrazino[3,2,1-jk]carbazol-3-yl)-; Pyrazino[3,2,1-jk]carbazole-3-ethanone derivative
EINECS	Contact for details

Quality Control

Our 2-Chloro-1-(8-Methyl-1,2,3A,4,5,6-Hexahydro-Pyrazino[3,2,1-Jk]Carbazol-3-Yl)-Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5% Total impurities ≤ 1.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.