Description

1,2,3,4,4A,7,8,8A-Octahydro-5-(Hydroxymethyl)-γ,1,2,4A-Tetramethyl-1-Naphthalene-1-Pentanol is a complex, high-purity synthetic intermediate characterized by its multi-ring, hydrogenated naphthalene core with hydroxyl and pentanol functional groups. This compound matters as a versatile chiral building block for the synthesis of advanced pharmaceutical actives and fine chemicals, offering a structurally defined scaffold for complex molecular construction. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty fragrance industries seeking to develop novel therapeutic agents or high-value specialty products.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of steroidal analogs, complex terpenoid-based therapeutics, and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and plant growth regulators that require specific stereochemistry.
• Fine Chemical Production: Serves as a sophisticated starting material or intermediate for manufacturing high-value specialty chemicals and catalysts.
• Fragrance & Flavor Chemistry: Acts as a potential intermediate for creating complex, long-lasting musk or amber scent molecules due to its polycyclic structure.
• Material Science Research: Investigated as a monomer or modifying agent for synthesizing novel polymers with specific thermal or mechanical properties.
• Academic & Industrial R&D: Employed in methodological studies and as a reference standard in asymmetric synthesis and natural product chemistry.

Basic Information

Product Name	1,2,3,4,4A,7,8,8A-Octahydro-5-(Hydroxymethyl)-γ,1,2,4A-Tetramethyl-1-Naphthalene-1-Pentanol
CAS No.	28644-71-5
Molecular Formula	C20H36O2
Molecular Weight	308.50 g/mol
Synonyms	5-(Hydroxymethyl)-γ,1,2,4a-tetramethyl-1,2,3,4,4a,7,8,8a-octahydro-1-naphthalenepentanol; (1R,2R,4aR,8aS)-5-(Hydroxymethyl)-1,2,4a-trimethyl-6-methylidene-3,4,5,7,8,8a-hexahydro-2H-naphthalen-1-ol (related stereoisomer); Tetramethyloctahydronaphthalenepentanol; A potential intermediate for Ambroxide synthesis; Polycyclic terpene alcohol derivative.
EINECS	Contact for details

Quality Control

Our 1,2,3,4,4A,7,8,8A-Octahydro-5-(Hydroxymethyl)-γ,1,2,4A-Tetramethyl-1-Naphthalene-1-Pentanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material may be hygroscopic (moisture-sensitive); keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (or as specified)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.