Description

(3As,9Bβ)-3A,4,5,6,6A,7,8,9,9A,9B-Decahydro-9α-Acetoxy-9Aα-Acetoxymethyl-6Aβ-Hydroxy-6α-Methyl-3-Methyleneazuleno[4,5-B]Furan-2(3H)-One is a complex, high-purity sesquiterpene lactone derivative with a unique azulene-fused furanone structure. This compound is valued for its intricate molecular architecture, which serves as a critical advanced intermediate in the synthesis of novel bioactive molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for lead compound optimization and the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of potential drug candidates, particularly in anti-inflammatory and anticancer research.
• Agrochemical Research: Used in the development of new, high-value plant protection agents and bio-pesticides due to its sesquiterpenoid core.
• Organic Synthesis Reference Standard: Serves as a high-purity standard for analytical method development and structural verification in complex natural product chemistry.
• Academic & Institutional Research: Employed in chemical biology studies to investigate structure-activity relationships (SAR) and novel reaction pathways.
• Fine Chemical Production: Acts as a precursor for the manufacture of specialized flavors, fragrances, and other high-value fine chemicals.

Basic Information

Product Name	(3As,9Bβ)-3A,4,5,6,6A,7,8,9,9A,9B-Decahydro-9α-Acetoxy-9Aα-Acetoxymethyl-6Aβ-Hydroxy-6α-Methyl-3-Methyleneazuleno[4,5-B]Furan-2(3H)-One
CAS No.	28587-46-4
Molecular Formula	C20H26O6
Molecular Weight	362.42 g/mol
Synonyms	9α-Acetoxy-9aα-acetoxymethyl-6aβ-hydroxy-6α-methyl-3-methylenedecahydroazuleno[4,5-b]furan-2(3H)-one; 6aβ-Hydroxy-6α-methyl-3-methylenedecahydro-9α-acetoxy-9aα-acetoxymethylazuleno[4,5-b]furan-2(3H)-one; Parthenolide derivative; Azuleno[4,5-b]furan-2(3H)-one, 3a,4,5,6,6a,7,8,9,9a,9b-decahydro-9α-acetoxy-9aα-(acetoxymethyl)-6aβ-hydroxy-6α-methyl-3-methylene-, (3aR,6S,6aR,9R,9aR,9bS)-rel-; Sesquiterpene lactone intermediate.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols. Every batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.