Description

4-Acetoxy-2-Azetidinone is a high-value β-lactam derivative, a crucial advanced intermediate in the synthesis of complex pharmaceutical compounds. Its significance lies in its role as a versatile building block for constructing novel antibiotics and other bioactive molecules, enabling precise chemical modifications. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries focused on developing next-generation antimicrobial agents and specialized organic synthesis.

Application

• Key Intermediate for Antibiotic Synthesis: Serves as a critical precursor in the production of carbapenem and penem class antibiotics, such as meropenem and ertapenem.
• Pharmaceutical Research & Development: Used as a specialized building block in medicinal chemistry for creating novel β-lactam structures with targeted biological activity.
• Fine Chemical Manufacturing: Employed in the synthesis of complex, high-value organic molecules requiring the protected azetidinone core.
• Process Chemistry & Scale-Up: Utilized in optimizing synthetic routes for the commercial production of active pharmaceutical ingredients (APIs).
• Academic & Industrial Research: A valuable reagent for studying β-lactam chemistry, ring-opening reactions, and the development of new synthetic methodologies.

Basic Information

Product Name	4-Acetoxy-2-Azetidinone
CAS No.	28562-53-0
Molecular Formula	C5H7NO3
Molecular Weight	129.11 g/mol
Synonyms	4-Acetoxyazetidin-2-one; 4-Acetoxy-2-azetidinone; 2-Azetidinone, 4-(acetyloxy)-; 4-(Acetyloxy)-2-azetidinone; 4-Acetoxyazetidinone; N-Acetyl-3-hydroxyazetidin-2-one; 3-Hydroxyazetidin-2-one acetate
EINECS	Contact for details

Quality Control

Our 4-Acetoxy-2-Azetidinone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for pharmaceutical intermediate applications. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling. A Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.