Description

4-(2-Hydroxyethyl)-Piperazine-1-Carboxamidine Hemisulfate is a high-purity chemical building block and reagent of significant importance in advanced organic synthesis. Its core value lies in its functional piperazine and amidine groups, which are pivotal for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where it serves as a key intermediate in the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological and cardiovascular diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Bioconjugation Reagent: Functions as a linker or modifying agent in the development of bioconjugates, probes, and diagnostic agents.
• Polymer Chemistry: Serves as a monomer or cross-linking agent for creating specialty polymers with tailored properties.
• Chemical Research: A versatile reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries.
• Ligand Synthesis: Used in the preparation of complexing agents and ligands for catalysis and metal ion sequestration.

Basic Information

Product Name	4-(2-Hydroxyethyl)-Piperazine-1-Carboxamidine Hemisulfate
CAS No.	28457-23-0
Molecular Formula	C7H16N4O · ½ H2SO4
Molecular Weight	226.25 g/mol (free base: 172.23 g/mol)
Synonyms	1-Carbamimidoyl-4-(2-hydroxyethyl)piperazin-1-ium sulfate (1:0.5); 2-[4-(Aminoiminomethyl)piperazin-1-yl]ethanol hemisulfate; N-(2-Hydroxyethyl)-N'-amidinopiperazine hemisulfate; 4-(2-Hydroxyethyl)piperazine-1-carboximidamide hemisulfate; HEPC hemisulfate; Guanidine, N,N'-(1,4-piperazinediyl)bis-, hemisulfate salt (related); Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our 4-(2-Hydroxyethyl)-Piperazine-1-Carboxamidine Hemisulfate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent absorption of moisture, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.