Description

20-[(R)-4-Hydroxy-2,6,6-Trimethyl-1-Cyclohexen-1-Yl]-5,9,14,18-Tetramethyl-3,5,7,9,11,13,15,17,19-Icosanonen-2-One is a high-purity, long-chain polyunsaturated ketone derivative, a key intermediate in the synthesis of complex bioactive molecules. Its precise stereochemistry and functional groups make it an essential building block for advanced pharmaceutical and fine chemical research. This compound is primarily sought by R&D and production teams in the pharmaceutical, nutraceutical, and specialty chemical industries for developing novel therapeutic agents and high-value synthetic targets.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of retinoids, vitamin A analogs, and other complex therapeutic molecules targeting cellular receptors.
• Fine Chemical Synthesis: Serves as a versatile chiral building block for constructing complex natural products and specialty chemicals with specific stereochemical requirements.
• Nutraceutical Research: Used in the development of advanced carotenoid derivatives and other bioactive compounds for health supplement formulations.
• Cosmetic Actives: A key ingredient in the research and development of next-generation anti-aging and skin-renewal cosmetic actives.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying lipid signaling pathways and cellular processes.
• Material Science: Investigated as a monomer or additive for creating specialized polymers with unique optical or structural properties.

Basic Information

Product Name	20-[(R)-4-Hydroxy-2,6,6-Trimethyl-1-Cyclohexen-1-Yl]-5,9,14,18-Tetramethyl-3,5,7,9,11,13,15,17,19-Icosanonen-2-One
CAS No.	28368-09-4
Molecular Formula	C₃₃H₅₂O₂
Molecular Weight	480.77 g/mol
Synonyms	(3R)-3-Hydroxy-20-[(1R,4R)-4-hydroxy-2,6,6-trimethyl-1-cyclohexen-1-yl]-3,7,11,15-tetramethyl-1-icosen-10-one; 20-[(1R,4R)-4-Hydroxy-2,6,6-trimethyl-1-cyclohexen-1-yl]-5,9,14,18-tetramethyl-(3R)-3,5,7,9,11,13,15,17,19-icosanonen-2-one; All-trans-3-Hydroxy-20-(4-hydroxy-2,6,6-trimethyl-1-cyclohexen-1-yl)-3,7,11,15-tetramethyl-1-icosen-10-one; A key retinoid synthesis intermediate.
EINECS	Contact for details

Quality Control

Our 20-[(R)-4-Hydroxy-2,6,6-Trimethyl-1-Cyclohexen-1-Yl]-5,9,14,18-Tetramethyl-3,5,7,9,11,13,15,17,19-Icosanonen-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR for structural confirmation, and specific tests for residual solvents and heavy metals to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to prevent oxidation and degradation. Keep the container in a cool, dry, and well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange viscous oil or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Chiral Purity	≥ 98.0% ee (by Chiral HPLC)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.