Description

2,5-Piperazinedione,3-(2-Mercaptoethyl)-(8Ci) is a specialized heterocyclic compound featuring a piperazinedione core with a pendant mercaptoethyl functional group. This unique structure makes it a valuable intermediate for the synthesis of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily sought by R&D chemists and process development scientists working in medicinal chemistry, peptide mimetics, and the development of novel bioactive compounds. Its defined reactivity profile offers a strategic building block for introducing sulfur-containing motifs into target structures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially those requiring thioether or disulfide linkages.
• Peptidomimetic Research: Used to create non-natural amino acid analogs and constrained peptide scaffolds for drug discovery.
• Ligand Synthesis: Serves as a precursor for chelating agents or functional ligands in catalysis and material science.
• Bioconjugation Chemistry: The mercapto group enables site-specific conjugation strategies for labeling proteins or other biomolecules.
• Fine Chemical Synthesis: Intermediate for producing specialty chemicals with specific chiral or functional properties.
• Academic & Industrial R&D: Utilized in exploratory research to investigate new chemical reactions and synthesize novel molecular libraries.

Basic Information

Product Name	2,5-Piperazinedione,3-(2-Mercaptoethyl)-(8Ci)
CAS No.	28147-70-8
Molecular Formula	C6H10N2O2S
Molecular Weight	174.22 g/mol
Synonyms	3-(2-Mercaptoethyl)piperazine-2,5-dione; 1,4-Diazacyclohexane-2,5-dione, 3-(2-mercaptoethyl)-; 3-(2-Sulfanylethyl)piperazine-2,5-dione; 2,5-Diketopiperazine, 3-(2-mercaptoethyl)-; (R,S)-3-(2-Mercaptoethyl)-2,5-piperazinedione; 3-(2-Thioethyl)-2,5-diketopiperazine; DKP derivative, mercaptoethyl-; 28147-70-8 (CAS)
EINECS	Contact for details

Quality Control

Our 2,5-Piperazinedione,3-(2-Mercaptoethyl)-(8Ci) is produced under controlled conditions to ensure high purity and batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support cGMP and ISO compliant documentation for advanced research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.