Description

n-Isopropyl-4-[1-Oxo-3-(3,4,5-Trimethoxyphenyl)Allyl]Piperazine-1-Acetamide Maleate is a high-purity, non-racemic synthetic intermediate of significant interest in advanced pharmaceutical research and development. Its complex molecular architecture, featuring a piperazine-acetamide core linked to a trimethoxyphenyl allyl ketone moiety, makes it a valuable precursor for the synthesis of novel bioactive compounds. This product is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries focusing on oncology, neurology, and other therapeutic areas requiring sophisticated chemical building blocks.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly in oncology and CNS research.
• Chemical Reference Standard: Used for analytical method development, validation, and quality control in API manufacturing.
• Medicinal Chemistry Research: Serves as a key scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Process Development: Employed in scaling up synthetic routes for potential Active Pharmaceutical Ingredients (APIs).
• Academic & Institutional Research: Utilized in university and institutional labs for exploring new chemical entities and biological pathways.
• Custom Synthesis: Acts as a starting material for the custom synthesis of more complex, target-specific molecules for clients.

Basic Information

Product Name	n-Isopropyl-4-[1-Oxo-3-(3,4,5-Trimethoxyphenyl)Allyl]Piperazine-1-Acetamide Maleate
CAS No.	28044-40-8
Molecular Formula	C23H33N3O7 • C4H4O4
Molecular Weight	Contact for details
Synonyms	1-Isopropyl-4-[3-(3,4,5-trimethoxyphenyl)-2-propenoyl]piperazine-1-acetamide maleate; 4-[1-Oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]-N-(1-methylethyl)-1-piperazineacetamide (Z)-2-butenedioate; 28044-40-8; (E)-1-(4-(2-(Isopropylamino)-2-oxoethyl)piperazin-1-yl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-one maleate; Isopropyl 4-[1-oxo-3-(3,4,5-trimethoxyphenyl)allyl]piperazine-1-acetamide maleate.
EINECS	Contact for details

Quality Control

Our n-Isopropyl-4-[1-Oxo-3-(3,4,5-Trimethoxyphenyl)Allyl]Piperazine-1-Acetamide Maleate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and related substances, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.