Description

(R)-2,3-Dimethylbutanoicacid CAS NO 27855-05-6 is a high-purity, single-enantiomer chiral carboxylic acid, serving as a critical building block in asymmetric synthesis. Its value lies in its ability to impart stereochemical control in the production of advanced pharmaceutical intermediates and fine chemicals. This compound is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require optically pure starting materials for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in cardiovascular and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators where specific stereochemistry is crucial for bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric hydrogenation and carbon-carbon bond-forming reactions.
• Flavor and Fragrance Industry: Employed in the synthesis of stereodefined aroma chemicals and flavoring agents.
• Material Science: A building block for chiral monomers in the development of polymers with specific optical or mechanical properties.
• Academic and R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	(R)-2,3-Dimethylbutanoic acid
CAS No.	27855-05-6
Molecular Formula	C6H12O2
Molecular Weight	116.16 g/mol
Synonyms	(R)-(+)-2,3-Dimethylbutyric Acid; (R)-2,3-Dimethylbutanoic Acid; D-2,3-Dimethylbutanoic Acid; (2R)-2,3-Dimethylbutanoic Acid; (R)-2,3-Dimethylbutyric Acid; (R)-α,β-Dimethylbutyric Acid; (R)-2,3-Dimethylbutanoicacid
EINECS	Contact for details

Quality Control

Our (R)-2,3-Dimethylbutanoic acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided and available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability, although the product is stable at room temperature for shorter periods. The container must be kept tightly sealed due to the compound's nature as a strong acid/organic solvent.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.