Description

Methyl 3-Chloro-2-Pyrazinecarboxylate is a versatile and high-value heterocyclic building block essential for advanced organic synthesis. Its core value lies in its bifunctional reactivity, featuring both an electrophilic chloro substituent and an ester group, making it a critical intermediate for constructing complex nitrogen-containing molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates, particularly those with pyrazine or pyrazinamide cores, such as potential antitubercular, anticancer, or CNS-active agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the pyrazine moiety contributes to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands or organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers, due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom chemical synthesis services catering to the needs of biotechnology and specialty chemical industries.

Basic Information

Product Name	Methyl 3-Chloro-2-Pyrazinecarboxylate
CAS No.	27825-21-4
Molecular Formula	C6H5ClN2O2
Molecular Weight	172.57 g/mol
Synonyms	3-Chloro-2-pyrazinecarboxylic acid methyl ester; Methyl 3-chloropyrazine-2-carboxylate; 2-Pyrazinecarboxylic acid, 3-chloro-, methyl ester; 3-Chloro-2-(methoxycarbonyl)pyrazine; 3-Chloropyrazine-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Chloro-2-Pyrazinecarboxylate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.