Description

Methyl 3-Hydroxypyrazine-2-Carboxylate is a versatile heterocyclic building block and key synthetic intermediate prized for its functionalized pyrazine core. This compound is essential for the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals, where its structure enables precise molecular modifications. It is primarily sought after by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in medicinal chemistry and custom synthesis projects.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug molecules, particularly those targeting neurological and metabolic disorders.
• Agrochemical Research: Used in developing new generations of herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Fluorescent Probe Development: Its heterocyclic structure is utilized in constructing molecular probes for biochemical sensing and imaging.
• Academic & Contract Research: Employed in university and CRO laboratories for exploratory chemistry and method development.
• Fine Chemical Production: Integrated into multi-step synthesis processes for producing high-value, specialized chemicals.

Basic Information

Product Name	Methyl 3-Hydroxypyrazine-2-Carboxylate
CAS No.	27825-20-3
Molecular Formula	C6H6N2O3
Molecular Weight	154.12 g/mol
Synonyms	Methyl 3-hydroxypyrazine-2-carboxylate; 3-Hydroxypyrazine-2-carboxylic acid methyl ester; Methyl 3-oxo-3,4-dihydropyrazine-2-carboxylate; 2-Pyrazinecarboxylic acid, 3-hydroxy-, methyl ester; 3-Hydroxy-2-pyrazinecarboxylic acid methyl ester; Methyl 3-hydroxypyrazinecarboxylate; 27825-20-3
EINECS	Contact for details

Quality Control

Our Methyl 3-Hydroxypyrazine-2-Carboxylate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.