Description

8-Azabicyclo(3.2.1)octane, 3-bromo-8-methyl-, endo- is a specialized bicyclic organic compound featuring a brominated tropane-like scaffold, serving as a valuable advanced pharmaceutical intermediate and a versatile building block in synthetic organic chemistry. Its unique bridged structure and halogen substitution make it a critical precursor for the development of complex molecules with potential biological activity. This compound is primarily utilized by research institutions and pharmaceutical R&D departments engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting the central nervous system.
• Medicinal Chemistry Research: Used in the design and synthesis of novel drug candidates, especially those based on tropane or nortropane alkaloid frameworks.
• Chemical Synthesis: Serves as a versatile electrophilic synthon for introducing the 3-bromo-8-methyl-8-azabicyclo[3.2.1]octane moiety into more complex molecular architectures.
• Ligand and Catalyst Development: Potential precursor for creating chiral ligands or organocatalysts due to its rigid, three-dimensional structure.
• Academic Research: Employed in universities and research institutes for studying reaction mechanisms and developing new synthetic methodologies.
• Reference Standard: Used as an analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	8-Azabicyclo(3.2.1)octane, 3-bromo-8-methyl-, endo-
CAS No.	27809-79-6
Molecular Formula	C8H14BrN
Molecular Weight	204.11 g/mol
Synonyms	3-Bromo-8-methyl-8-azabicyclo[3.2.1]octane (endo-); endo-3-Bromo-8-methyl-8-azabicyclo[3.2.1]octane; 8-Methyl-3-bromo-8-azabicyclo[3.2.1]octane; Tropane, 3-bromo-8-methyl-; 3-Bromo-8-methylnortropane; 27809-79-6; 8-Azabicyclo[3.2.1]octane, 3-bromo-8-methyl-
EINECS	Contact for details

Quality Control

Our 8-Azabicyclo(3.2.1)octane, 3-bromo-8-methyl-, endo- is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.