Description

tert-Butyl Diethylphosphonoacetate is a high-value organophosphorus compound widely used as a key synthetic intermediate in organic chemistry. This compound is essential for performing the Horner-Wadsworth-Emmons (HWE) olefination reaction, enabling the efficient and stereoselective construction of carbon-carbon double bonds. It is a critical reagent for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where precise molecular assembly is required.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs), particularly those containing α,β-unsaturated carbonyl moieties.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators that require specific alkene geometries.
• Fine Chemical Manufacturing: Serves as a versatile reagent for the synthesis of complex organic molecules, flavors, and fragrances.
• Material Science Research: Employed in the development of novel polymers, liquid crystals, and organic electronic materials via controlled olefination.
• Academic & R&D Laboratories: A staple reagent for methodological development in organic synthesis and catalysis studies.

Basic Information

Product Name	tert-Butyl Diethylphosphonoacetate
CAS No.	27784-76-5
Molecular Formula	C10H21O5P
Molecular Weight	252.24 g/mol
Synonyms	Diethyl (tert-butoxycarbonylmethyl)phosphonate; (tert-Butoxycarbonylmethyl)phosphonic Acid Diethyl Ester; Diethyl [(tert-butoxy)carbonyl]methylphosphonate; Phosphonoacetic Acid, tert-Butyl Ester, Diethyl Ester; Acetic Acid, Phosphono-, 1,1-Dimethylethyl Ester, Diethyl Ester; HWE Reagent; Horner-Wadsworth-Emmons Reagent
EINECS	Contact for details

Quality Control

Our tert-Butyl Diethylphosphonoacetate is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including NMR, GC, and HPLC, to ensure high chemical purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.