Description

n-(Bis(4-Fluorophenyl)Methyl)Piperazine Dihydrochloride is a high-purity, fluorinated piperazine derivative supplied as a dihydrochloride salt. This compound serves as a critical pharmaceutical intermediate and versatile building block in advanced organic synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and psychiatric drug candidates.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its fluorinated aromatic structure.
• Chemical Synthesis: Acts as a versatile precursor for creating complex molecules in medicinal chemistry and material science research.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal complexation studies.
• Life Science Research: Utilized in biochemical and pharmacological research as a tool compound for target validation and mechanism-of-action studies.

Basic Information

Product Name	n-(Bis(4-Fluorophenyl)Methyl)Piperazine Dihydrochloride
CAS No.	27758-39-0
Molecular Formula	C18H20F2N2·2HCl
Molecular Weight	383.28 g/mol
Synonyms	1-[(Bis(4-fluorophenyl)methyl]piperazine dihydrochloride; 1-[Bis(4-fluorophenyl)methyl]piperazine hydrochloride (1:2); 1-[(4,4'-Difluorobenzhydryl)]piperazine dihydrochloride; 4,4'-Difluorobenzhydryl piperazine dihydrochloride; Bis(4-fluorophenyl)(piperazin-1-yl)methane dihydrochloride; 27758-39-0 (CAS); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our n-(Bis(4-Fluorophenyl)Methyl)Piperazine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.