Description

3-Dehydroshikimate is a key biochemical intermediate in the shikimate pathway, essential for the biosynthesis of aromatic amino acids and numerous secondary metabolites. Its high purity and stability are critical for research and development in metabolic engineering and pharmaceutical synthesis. This compound is primarily utilized by researchers in biochemistry, biotechnology, and pharmaceutical development for studying enzyme kinetics, pathway regulation, and as a precursor for more complex molecules.

Application

• Biochemical Research: Used as a standard and substrate in enzymatic assays to study the shikimate pathway, particularly for enzymes like 3-dehydroquinate dehydratase and shikimate dehydrogenase.
• Metabolic Engineering: Serves as a crucial intermediate for the microbial production of high-value compounds like shikimic acid, a key precursor for the antiviral drug oseltamivir (Tamiflu®).
• Pharmaceutical Development: Acts as a building block in the synthesis of novel pharmaceuticals and fine chemicals that target aromatic amino acid biosynthesis.
• Academic Research: Employed in university and institutional labs for fundamental studies on plant and microbial metabolism.
• Enzyme Inhibitor Screening: Utilized in high-throughput screening assays to identify potential herbicides or antimicrobial agents that target the shikimate pathway.
• Diagnostic Reagent Manufacturing: Can be incorporated into diagnostic kits for measuring specific enzyme activities in clinical or agricultural samples.

Basic Information

Product Name	3-Dehydroshikimate
CAS No.	27655-56-7
Molecular Formula	C7H8O6
Molecular Weight	188.13 g/mol
Synonyms	3-Dehydroshikimic Acid; (3R,4R)-3,4-Dihydroxy-5-oxocyclohex-1-ene-1-carboxylic Acid; 5-Dehydroshikimate; 3,4-Didehydroshikimate; NSC 163184; 3-DHS; DHS
EINECS	Contact for details

Quality Control

Our 3-Dehydroshikimate is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR for structural confirmation, and residual solvent analysis to ensure it meets the exacting standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a desiccated environment to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.