Description

Diflunisal CAS NO 27494-42-4 is a non-steroidal anti-inflammatory drug (NSAID) belonging to the salicylate class, functioning as a potent cyclooxygenase (COX) inhibitor. This compound is valued for its extended duration of action and efficacy in managing pain and inflammation. It is a critical active pharmaceutical ingredient (API) primarily required by pharmaceutical manufacturers for the production of prescription analgesic and anti-inflammatory medications.

Application

• Pharmaceutical API: Primary use as the active ingredient in solid oral dosage forms such as tablets and capsules for pain relief.
• Analgesic Formulations: Used in medications for the management of mild to moderate pain, including postoperative pain.
• Anti-inflammatory Therapies: Incorporated into treatments for chronic inflammatory conditions like osteoarthritis and rheumatoid arthritis.
• Research & Development: Serves as a key reference standard and intermediate in pharmacological and pharmacokinetic studies.
• Veterinary Medicine: Potential application in veterinary pharmaceuticals for pain management in animals.
• Chemical Synthesis: Acts as a chemical intermediate for the synthesis of more complex salicylate derivatives.

Basic Information

Product Name	Diflunisal
CAS No.	27494-42-4
Molecular Formula	C13H8F2O3
Molecular Weight	250.20 g/mol
Synonyms	2',4'-Difluoro-4-hydroxy-3-biphenylcarboxylic acid; 5-(2,4-Difluorophenyl)salicylic acid; Dolobid; MK-647; Diflunisalum; UNII-O6XG8B6IUK; Fluniget
EINECS	248-485-8

Quality Control

Our Diflunisal is manufactured under strict quality systems to meet the rigorous standards of the pharmaceutical industry. We provide material that complies with major pharmacopoeial specifications, including USP and EP monographs. Every batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles to ensure traceability and regulatory compliance for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to protect from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF Titration)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.