Description

2-[4-(4-Fluorophenyl)Piperazin-1-Yl]Ethanamine is a high-purity, functionalized piperazine derivative of significant interest in advanced organic synthesis. This compound matters as a versatile and critical building block for constructing complex molecules with tailored pharmacological properties. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targets.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential antipsychotic, antidepressant, and anxiolytic drug candidates.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry programs, enabling structure-activity relationship (SAR) studies.
• Ligand Synthesis: Used in the preparation of selective ligands for serotonin (5-HT) and dopamine receptor subtypes.
• Fine Chemical Manufacturing: Employed in the multi-step synthesis of complex, high-value specialty chemicals.
• Reference Standard: Supplied as a certified reference material for analytical method development and quality control in API production.

Basic Information

Product Name	2-[4-(4-Fluorophenyl)Piperazin-1-Yl]Ethanamine
CAS No.	27144-84-9
Molecular Formula	C12H18FN3
Molecular Weight	223.29 g/mol
Synonyms	1-(2-Aminoethyl)-4-(4-fluorophenyl)piperazine; N-(2-Aminoethyl)-4-(4-fluorophenyl)piperazine; 4-(4-Fluorophenyl)-1-piperazineethanamine; 2-(4-(4-Fluorophenyl)piperazin-1-yl)ethan-1-amine; 4-(p-Fluorophenyl)-1-(2-aminoethyl)piperazine; 1-(4-Fluorophenyl)-4-(2-aminoethyl)piperazine; 27144-84-9
EINECS	Contact for details

Quality Control

Every batch of 2-[4-(4-Fluorophenyl)Piperazin-1-Yl]Ethanamine is manufactured and tested under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards for research and pharmaceutical intermediates. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.