Description

1-(Toluene-4-Sulfonyl)-Piperazine is a versatile sulfonamide derivative and a key organic building block used in advanced chemical synthesis. This compound matters for its role as a crucial intermediate in the development of active pharmaceutical ingredients (APIs) and other high-value specialty chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides, leveraging the piperazine moiety for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Employed as a monomer or cross-linking agent in the synthesis of specialty polymers with tailored properties.
• Chemical Research & Development: A valuable reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in academic and industrial labs.
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of certain specialty dyes and colorants.

Basic Information

Product Name	1-(Toluene-4-Sulfonyl)-Piperazine
CAS No.	27106-51-0
Molecular Formula	C11H16N2O2S
Molecular Weight	240.32 g/mol
Synonyms	1-(p-Toluenesulfonyl)piperazine; 4-Methyl-N-(piperazin-1-yl)benzenesulfonamide; N-(Piperazinyl)-4-toluenesulfonamide; p-Toluenesulfonylpiperazine; Tosylpiperazine; 1-Tosylpiperazine; 1-(4-Tolylsulfonyl)piperazine; 4-Methylbenzenesulfonyl piperazine
EINECS	Contact for details

Quality Control

Our 1-(Toluene-4-Sulfonyl)-Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) documenting full specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in the original packaging or an opaque secondary container.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.