Description

1-[(4-Fluorophenyl)Sulfonyl]Piperazine is a high-purity, functionalized piperazine derivative, serving as a critical building block in advanced organic synthesis. This compound is valued for its sulfonyl and fluorophenyl groups, which are instrumental in modulating the physicochemical and biological properties of target molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the fluorophenylsulfonyl moiety can enhance activity and environmental stability.
• Ligand and Catalyst Development: Employed in organometallic chemistry and catalysis research to construct complex ligands for transition metal complexes.
• Polymer Science: Acts as a monomer or cross-linking agent in the synthesis of specialty polymers with tailored thermal and mechanical properties.
• Chemical Research: Serves as a versatile scaffold in academic and industrial R&D for exploring new chemical reactions and synthesizing novel heterocyclic compounds.
• Material Science: Utilized in the development of advanced organic electronic materials, such as charge-transport layers or photoactive components.

Basic Information

Item	Details
Product Name	1-[(4-Fluorophenyl)Sulfonyl]Piperazine
CAS No.	27106-49-6
Molecular Formula	C10H13FN2O2S
Molecular Weight	244.29 g/mol
Synonyms	1-(4-Fluorobenzenesulfonyl)piperazine; 4-Fluorophenyl piperazin-1-yl sulfone; N-(4-Fluorophenylsulfonyl)piperazine; 4-Fluorobenzenesulfonylpiperazine; 1-(p-Fluorophenylsulfonyl)piperazine; Piperazine, 1-[(4-fluorophenyl)sulfonyl]-; 27106-49-6
EINECS	Contact for details

Quality Control

Our 1-[(4-Fluorophenyl)Sulfonyl]Piperazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for pharmaceutical and advanced chemical synthesis. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.